Chinese Grand Pharma backs Dutch medtech Xeltis with €15m

Chinese Grand Pharma backs Dutch medtech Xeltis with €15m

Published: 10-08-2022 12:27:00 | By: Pie Kamau | hits: 262 | Tags:

Xeltis, a medtech company developing the most advanced polymer-based restorative cardiovascular devices, announced that a Chinese company, Grand Pharmaceutical Group, has committed to invest €15 million in equity and license fees, as a cornerstone funding for its ongoing Series D2 financing round.

The Grand Pharma commitment comprises an equity investment and product license, representing Xeltis’ first commercial deal and its first funding from an Asian company. The agreement, which focuses mainly on the Xeltis’ restorative hemodialysis access device aXess, also involves other new products in the field of hemodialysis developed under the same technology platform. Grand Pharma will also have exclusive rights of development, production and commercialization, as well as pre-emptive negotiation right for Xeltis’ products developed in other indications in the Greater China region.

Eliane Schutte, CEO, Xeltis: “Grand Pharma’s commitment to invest in Xeltis brings global validation of aXess’ commercial potential from one of the largest Chinese life sciences companies, from the country with the largest need of hemodialysis access globally. It confirms the strength of our technology platform and clinical evidence to date, and supports our goal of providing potentially more durable, transformative restorative devices for patients worldwide.”

aXess is a first-of-its-kind restorative cardiovascular access graft for patients with chronic kidney disease (CKD) requiring hemodialysis. China has the largest number of CKD patients in the world, accounting for about 130 million people, of which around 580,000 are currently on hemodialysis. The number of people on hemodialysis in China is projected to increase by 15 percent in the next five years. 

Frank Zhou, CEO, Grand Pharmaceutical Group: “Grand Pharma is building interventional diagnosis and treatment platform for cardiovascular and cerebrovascular diseases in China. Xeltis’ aXess device would represent an excellent addition to the scope of our broad portfolio and expected to bring significant clinical impact in China.” 

The aXess graft enables early puncturing, or initiation of dialysis, working like some of currently available ePTFE synthetic hemodialysis access grafts. In addition, it is designed to turn into a patient’s own living blood vessel, like an arteriovenous fistula. Once implanted, its biocompatible, porous microstructure gets naturally colonized by the patient’s own tissue, which overtime takes over functionality before the original device absorbs in the body. This process is called endogenous tissue restoration (ETR).

www.xeltis.com
www.chinagrandpharm.com